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Tetrahydrocannabinolic Acid (THCA) is the main constituent in raw cannabis. THCA converts to THC when burned, vaporized, or heated for a period of time at a certain temperature. THCA, CBDA, CBGA and other acidic cannabinoids hold the most COX-1 and COX-2 inhibition for the anti-inflammatory properties that cannabis has to offer. THCA also acts as an anti-proliferative and anti-spasmodic.